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Search Results for " renal diseases "

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天然化合物

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T7714	Temocapil		Tyrosinase
	Temocapril is an inhibitor of tyrosine kinase.		Tyrosinase
T6698	Temocapril hydrochloride	CS-622 HCl,Acecol,Temocapril HCl,CS-622	RAAS
	Temocapril hydrochloride (CS-622 HCl), the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension.		RAAS
T50000	2-Iodohippuric Acid		Others
	2-Iodohippuric Acid can be used to measure renal clearance for renal function studies, and for the diagnosis of certain diseases, such as liver and kidney disease. In addition, it is used in the synthesis of certain drug...		Others
T1182	Levocarnitine propionate hydrochloride	Propionyl-L-carnitine hydrochloride,L-Propionylcarnitine chloride,ST-261	Histamine Receptor
	Levocarnitine propionate hydrochloride (ST-261) is used for the treatment of the deterioration of renal function, congestive heart failure, intermittent claudication, and other diseases.		Histamine Receptor
T16808	Runcaciguat		Others , Guanylate cyclase
	Runcaciguat is an orally active stimulator of soluble guanylate cyclase.		Others , Guanylate cyclase
T8366	Mitochonic acid 5	MA-5	Mitochondrial Metabolism
	Mitochonic acid 5 (MA-5) is a derivative of the plant hormone indole-3-acetic acid. Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocyte damage.It has been shown to improve survival of f...		Mitochondrial Metabolism
T11412	IPN60090	GLS1-IN-1	Others , transporter
			Others , transporter
T39611	Enuvaptan	Enuvaptan,BAY-2327949
	Enuvaptan is a vasopressin receptor antagonist and has the potential for research into renal and cardiovascular diseases.
T71450	Ilacirnon sodium
	Ilacirnon sodium is a potent CCR2 antagonist that may be useful in the treatment of renal diseases including Focal Segmental Glomerulosclerosis and Diabetic Nephropathy.
T76762	Tabalumab
	Tabalumab (LY2127399), a humanized monoclonal antibody (IgG4 type) targeting B-cell activating factor (BAFF), exhibits neutralizing activity against both membrane-bound and soluble BAFF. This compound is relevant for res...
T70990	ADMA-d6
	NG,NG-dimethyl-L-arginine-d6 (ADMA-d6) (hydrochloride) is intended for use as an internal standard for the quantification of NG,NG-dimethyl-L-arginine by GC- or LC-MS. ADMA is an endogenous inhibitor of nitric oxide synt...

Compounds

Temocapril hydrochloride

T6698

Synonym: CS-622 HCl,Acecol,Temocapril HCl,CS-622

Levocarnitine propionate hydrochloride

T1182

Synonym: Propionyl-L-carnitine hydrochloride,L-Propionylcarnitine chloride,ST-261

Target: Histamine Receptor

Runcaciguat

T16808

Synonym:

Target: Others, Guanylate cyclase

Mitochonic acid 5

T8366

Synonym: MA-5

Target: Mitochondrial Metabolism

IPN60090

T11412

Synonym: GLS1-IN-1

Target: Others, transporter

Enuvaptan

T39611

Synonym: Enuvaptan,BAY-2327949

カタログ番号	製品名	別名	ターゲット
T8053	N-Acetyl-L-arginine	Ac-Arg-OH	Endogenous Metabolite
	N-Acetyl-L-arginine (Ac-Arg-OH) belongs to the class of organic compounds known as n-acyl-l-alpha-amino acids. These are n-acylated alpha amino acids which have the L-configuration of the alpha-carbon atom. N-a-Acetyl-L-...		Endogenous Metabolite
TN3753	Dalbergioidin		Tyrosinase , ROS , Akt , PI3K , TGF-beta/Smad
	Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces bikiniensis that has commonly been used as an indicator or...		Tyrosinase , ROS , Akt , PI3K , TGF-beta/Smad

天然物製品

N-Acetyl-L-arginine

T8053

Synonym: Ac-Arg-OH

Target: Endogenous Metabolite

Dalbergioidin

TN3753

Synonym:

Target: Tyrosinase, ROS, Akt, PI3K, TGF-beta/Smad

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04483	IRAK4 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4...
TMPY-00261	Meprin beta Protein, Human, Recombinant (His)	Human	HEK293 Cells
	MEP1B (Meprin A Subunit Beta) is a Protein Coding gene. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the me...
TMPJ-00332	TPA Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Tissue-type plasminogen activator (PLAT) is a protein that secreted into extracellular space. PLAT contains five domains: EGF-like domain, fibronectin type-I domain, 2 kringle domains and peptidase S1 domain. It belongs...

IRAK4 Protein, Human, Recombinant (His)

TMPY-04483

Species: Human

Expression System: Baculovirus Insect Cells

Meprin beta Protein, Human, Recombinant (His)

TMPY-00261

Species: Human

Expression System: HEK293 Cells

tPA Protein, Human, Recombinant (His)

TMPJ-00332

Species: Human

Expression System: HEK293 Cells

カタログ番号	製品名
L8700	Ferroptosis Compound Library		779 compounds
	A unique collection of 779 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study；

ライブラリー

Ferroptosis Compound Library

L8700

Compounds: 779